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Manchester United welcome Manchester City to Old Trafford this weekend as they look to pull off the double over their inner-city rivals. Ruben Amorim's men secured a 2-1 victory over the Citizens at the Etihad earlier in the season, with Amad Diallo scoring a late winner. It is one of the only brightsparks in a campaign to forget for Man United, who are languishing in the bottom half of the table. Meanwhile, Man City are not going to be crowned champions again. They are so far off Liverpool, and their only aim is to ensure they are back in the Champions League next year by finishing in the top five. However, ahead of this match, both sides have plenty of issues. .. The choice for who starts in goal is pretty straightforward, given Altay Bayindir is injured so Andre Onana will start. Amorim favours a back three, but he is without Lisandro Martinez, Ayden Heaven and Jonny Evans. Matthijs de Ligt is almost certain to start, and given his experience, we could see Harry Maguire replace Leny Yoro. On the other side of the back three, Noussair Mazraoui is likely to keep his place. Since joining the Red Devils in January, Patrick Dorgu has impressed and looked lively, so he'll probably start on the left, with Diogo Dalot on the right. In midfield, Manuel Ugarte is establishing himself as one of the two starting centre players, and Casemiro should join him. Christian Eriksen is an option, while Bruno Fernandes can also play there, but it would be a surprise to see Amorim not elect for a more solid midfield base. Fernandes is likely to be in one of the two number ten positions, with Mason Mount and Alejandro Garnacho competing for the other. Mount has been injured for the majority of his time at Old Trafford, but he is now fit again and could thrive in Amorim's system. And up front, there is a straight choice between Rasmus Hojlund and Joshua Zirkzee. Neither are prolific goalscorers, but Hojlund has the pace to trouble Man City's high line, so expect to see him start. Ederson will be in goal for City after recovering his spot from Stefan Ortega. Pep Guardiola has plenty of defensive issues, with Nathan Ake, John Stones and Manuel Akanji all out until the end of the season. That means Ruben Dias is likely to partner Abukodir Khusanov in the heart of the defence. At right-back, he has a choice between Rico Lewis and Matheus Nunes, but given the fact City are away, we could see the former get the nod. At left-back, it will be Josko Gvardiol. Nico Gonzalez was signed in January as a Rodri-type replacement, and you can expect to see him in midfield. It will be a straight fight between Mateo Kovacic and Ilkay Gundogan for who partners him. The main issue in the forward areas is how to replace Erling Haaland. Guardiola confirmed he would be without his star striker for five to seven weeks, so they are going to have to adapt. It seems likely that Omar Marmoush will take the responsibility as the lead striker. There are then an abundance of attacking options to choose from. He has Phil Foden, Kevin De Bruyne, Bernardo Silva, Jack Grealish, Savinho and Jeremy Doku. All offer something different, but it would be a surprise if Foden and Bernardo weren't involved in some way, while on the left, we could see Doku get a start. This Premier League clash will take place on Sunday, April 6. Kick-off at Old Trafford is scheduled for 4: 30pm. The match will be shown on Sky Sports Main Event and Premier League. Sky Go customers can tune in via their laptops and mobile devices. Alternatively, fans can purchase a NOW TV pass. More info here. talk SPORT will have updates throughout the afternoon, and talk SPORT. com will have the action on our dedicated Premier League blog. To tune in to talk SPORT through the website,  click HERE for the live stream. You can also listen via the talk SPORT app, on DAB digital radio, through your smart speaker and on 1089 or 1053 AM. © 2025 talk SPORT Limited

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