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FPL Newcastle United will be without summer signings Yoane Wissa and Jacob Ramsey for the weekend visit of Wolverhampton Wanderers, although Nick Woltemade is set to make his debut. Wissa, the £50million-plus deadline-day addition from Brentford, will be sent for a scan to determine the extent of his problem, but Eddie Howe is unsure how long the 29-year-old will be sidelined for. Advertisement Ramsey is also set to be out until the October international break after suffering an ankle problem which forced him off during the 0-0 draw at Leeds United last month, meaning he will potentially miss seven games across all competitions, including Champions League clashes with Barcelona and Union Saint-Gilloise. Joelinton is back from a groin injury, which lessens the blow of losing Ramsey, though Wissa’s absence means that Woltemade, Newcastle’s €75m (£65m) club-record signing from Stuttgart, is in line to make his full debut against Wolves. “Unfortunately not, no, ” Howe said when asked if Wissa was available. “He won’t make this game. I saw him for the first time (on Thursday). He’s feeling the effects of the injury he had. We’ll have to see how he is. “I don’t know currently as I sit here (how long he’ll be out for). He’ll go away for tests and maybe see a specialist to see. Unfortunately I can’t give you an update. ” Wissa was brought in partly to lessen the immediate pressure on Woltemade, the 23-year-old Germany international, but now the latter is likely to be thrust into Premier League and Champions League action. “Yes, he’s fine, ” Howe said of Woltemade. “He’s trained well. I’ve been really, really pleased with how he’s trained. A big opportunity for him. He’s got a great nature, he’s a great character, he’s not looked out of place in training and showed his qualities. “I don’t think there’s a set formula for new players. It’s all to do with your need and your fitness and form. I have no hesitation in playing the new players. He’s big in size, but he’s not necessarily your traditional target man. He’s a very good manipulator of the ball. ” Ramsey, meanwhile, was forced off at half-time during his full Newcastle debut at Leeds with an ankle problem, which has proven to be more serious than it first appeared. Advertisement “Jacob Ramsey’s the only other injury concern we have, ” Howe said. “He’ll miss the game after suffering the tackle against Leeds. His ankle swelled up, he had to come off and unfortunately he’ll be out until probably the next international break. ” Howe also addressed Alexander Isak’s British-record, deadline-day £125m transfer to Liverpool for the first time. Although he did not name Liverpool — referring to them as “the other club” in one of his answers — Howe did use the word “strike” to describe Isak’s summer antics, which included refusing to train or play. The head coach admitted that, as soon as Isak intimated he did not want to be part of the group, their relationship irreversibly changed. “Alex and I always enjoyed a great relationship, I always enjoyed working with him, ” Howe said. “It was mutually beneficial and we helped him become the player he is today, he achieved some milestones and was part of a very successful team. “The moment he went on strike, our relationship did change and that’s probably a turning point our relationship took. “Communication became difficult from that point onwards. I won’t go into anymore than that. ” (Top image of Yoane Wissa: Serena Taylor/Newcastle United via Getty Images) Spot the pattern. Connect the terms Find the hidden link between sports terms Play today's puzzle Chris Waugh is a staff writer for The Athletic, covering North East football and most particularly Newcastle United. Before joining The Athletic he worked for Mail Online, and then reported on NUFC for The Chronicle, The Journal and The Sunday Sun. He has covered NUFC home and away since 2015. Follow Chris on Twitter @Chris DHWaugh