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When times have been tough in the past for Manchester City under Pep Guardiola, there has always been the sense that they will pull through; it will be OK. Almost to the extent there has been little dramatic tension around them, only inevitability. Not now. The City machine looks broken, the certainties that have driven them for so long absent, the control gone. They got exactly what they deserved here – another defeat, a sixth in seven matches in all competitions, and it is very difficult to see them defending their Premier League title. The delirious Liverpool crowd informed Guardiola that he would be sacked in the morning, which prompted him to raise six digits in their direction, one for each of his league titles in England. It was an isolated act of defiance from someone with the club’s crest on their chest. Liverpool were everything City were not; suffocating at the back, physical in every position, slick on the ball, menacing in front of goal. Cody Gakpo’s opener was scant reward for their initial dominance but it was never going to be an occasion when Arne Slot’s team did anything other than extend their lead over second-placed Arsenal to nine points. And put 11 points between themselves and City, who lag in fifth. Guardiola had admitted that his players were suffering, as is he, and there is no doubt that this is the biggest crisis of his City tenure. At least there is some jeopardy now. Mohamed Salah made the points safe for Liverpool from the penalty spot. The title is theirs to lose. City were 2-1 or longer to win with every bookmaker in England, the first time since Guardiola’s first season at the club in 2016-17 they had not been the favourites for a league game. City as the plucky underdogs? It went into the mix, as did Guardiola’s record at Anfield. Only once in nine previous visits in all competitions had his City team enjoyed victory – and that was when the ground was empty for the league fixture in the pandemic season of 2020-21. It was rocking here, the home crowd sensing blood and tasting it after 12 minutes. Nobody could say that the breakthrough was not advertised; moments earlier, Virgil van Dijk had hit the far post with a thumping header. Stefan Ortega, who Guardiola preferred in the City goal, looked to have got his fingertips to the ball. Trent Alexander-Arnold was the architect of the opener, moseying into midfield to ping a diagonal up the inside right for Salah, who had acres of space into which to run. City were exposed – and not for the last time in that area. Over came Manuel Akanji but Salah cut inside to curve over a beautiful low cross. Less beautiful from a City point of view was how Kyle Walker stopped and watched Gakpo attack the far post and tap home. It was the symbol of what was a horrible start by City and there were others: loose passes, just a basic timidity. The nerves had been written all over Guardiola’s features before kick-off. His players were edgy. It was the 25th minute before City strung a few passes together inside the Liverpool half and even then, they ended going all the way back to Ortega, red shirts hounding them every step of the way. Liverpool could have been further ahead by then because Van Dijk was guilty of heading off target from an Alexis Mac Allister corner. The captain was free; he seemed certain to score. Salah had won the corner after a foot-race with Nathan Aké following another lovely Alexander-Arnold pass; Salah had the City left-back for pace, Aké only just managing to get his foot in. The excellent Dominik Szoboszlai, who more than justified his selection ahead of Curtis Jones, had worked Ortega with a stinging drive in the early going and there was the moment when Liverpool won the ball high up and menaced through Luis Díaz and Alexander-Arnold. Gakpo stepped in to lift high. Sign up to Football Daily Kick off your evenings with the Guardian's take on the world of football after newsletter promotion City stabilised over the final 20 minutes of the first half, although it was jarring to see how low their threat levels were, particularly up the wings. They wanted extra touches and Liverpool were in no mood to give them time. City’s only flicker before the interval came on 39 minutes when Rico Lewis prodded wide of the far post from an Erling Haaland pass. Just before that, Alexander-Arnold had fizzed inches wide after a corner came out to him. Liverpool had further chances for the second after the restart, Matheus Nunes making a saving block to deny Gakpo and, from the resulting corner, Van Dijk flicking a header just over. A thought for City – maybe somebody mark the big man? Salah also blew a gilt-edged one-on-one with Ortega, firing high after Bernardo Silva had played a back pass to Akanji with directions to the Royal Liverpool Hospital on it. City got on the ball more in the second period. They tried to work their short passing game. It was an exercise in rebuilding confidence as much as exerting control. Jérémy Doku made a difference when Guardiola introduced him for Nunes on the left wing. And yet where were the chances? Liverpool continued to look the more dangerous team on the counter, Salah especially, and if their priority in the closing stages was to defend securely, then another goal would not hurt. It came when Rúben Dias dallied and Walker took a heavy touch, allowing Díaz to rob him and sprint away. When Ortega was late into the challenge with him, it was an obvious penalty, the only question being whether the goalkeeper would face censure. He did not, Salah’s penalty conversion punishment enough. There was time for Van Dijk to err and present the City substitute Kevin De Bruyne with a one-on-one against the underworked Caoimhín Kelleher. The goalkeeper blocked. For City, there is no way out of the torment.